Ischemic Vascular Disease, Nitric Oxide Deficiency, and Impaired Wound Healing
Joseph V. Boykin Jr., MD, FACS
Published in Nov/Dec 2006 Vascular Disease Management as a supplement

The objective of this study was to clinically evaluate the correlation between nitric oxide Bioactivity and wound repair in 12 patients with elevated homocysteine levels.

Increased Cutaneous Sensibility in Patients with Diabetic Neuropathy Utilizing a Pharmacological Approach-- Clinical Case Evidence
Mackie J. Walker Jr., DPM, and Lauren M. Morris, PMAC
Published in May/June 2007 Vascular Disease Management as a supplement

The following case reports illustrate the successful use of Metanx® in treating Diabetic Peripheral Neuropathy and the pain associated with it.


April 2006 issue of 'WOUNDS'

CME Article featured in the April 2006 issue of WOUNDS
Homocysteine– A Stealth Mediator of Impaired Wound Healing: A Preliminary Study - Joseph V. Boykin, Jr., MD, and Chris Baylis, PhD

The objective of this study was to clinically evaluate the amino acid homocysteine (Hcy) as a risk factor for impaired wound healing in 12 patients receiving topical human fibroblast-derived dermal substitute treatment for nonhealing lower-extremity wounds.

ACPE/CME/CPME Accredited
WOUNDS is published by HMP Communications


Click here to view a Compendium of Clinical Cases and Clinical Decision Making titled "A Breakthrough Medical Approach in the Management of Patients with Diabetic Neuropathy."

Vascular Disease Management

This information was published in the December 2005 issue of Vascular Disease Management and Podiatry Today as a supplement.

Vascular Disease Management and Podiatry Today are published by HMP Communications.


Metanx® features L-Methylfolate (Metafolin®), the active form of Folate.

  • Up to 50% of patients are unable to fully convert folic acid into the active form of folate, L-methylfolate.
  • There is no conversion required with L-methylfolate.

Metanx® has a unique formulation providing your patients the active forms of folate, vitamin B6 and vitamin B12.

Each Metanx® tablet contains:

L-methylfolate (Metafolin®)
2.8 mg
Pyridoxal 5'-phosphate
25 mg
Methylcobalamin
2 mg


Click here for a price quote